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What is guided-diffusion?

openai/guided-diffusion — explained in plain English

Analysis updated 2026-06-24

7,369PythonAudience · researcherComplexity · 5/5Setup · hard

In one sentence

OpenAI's 2021 research code for generating high-quality images using diffusion models with classifier guidance, includes pre-trained models at multiple resolutions and scripts to run or train your own.

Mindmap

mindmap
  root((repo))
    What it does
      AI image generation
      Beats GANs in quality
    Key technique
      Classifier guidance
      Noise removal steps
      Guidance scale control
    Pre-trained models
      64 to 512 pixel sizes
      Upsampler models
      LSUN scene models
    Usage
      Download weights
      Run Python scripts
      Command-line flags
    Tech stack
      Python
      PyTorch
      CUDA GPU
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Code map

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filefunction / class

What do people build with it?

USE CASE 1

Generate images at 64x64 to 512x512 resolution using pre-trained diffusion models with classifier guidance to steer output toward a target category.

USE CASE 2

Train your own diffusion model or image classifier on a custom dataset using the provided training scripts.

USE CASE 3

Upscale low-resolution generated images to higher resolution using the included upsampler models.

What is it built with?

PythonPyTorchCUDA

How does it compare?

openai/guided-diffusionbelluzj/fantasque-sanspython-visualization/folium
Stars7,3697,3687,368
LanguagePythonPythonPython
Setup difficultyhardeasyeasy
Complexity5/51/52/5
Audienceresearcherdeveloperdata

Figures from each repo's GitHub metadata at analysis time.

How do you get it running?

Difficulty · hard Time to first run · 1day+

Requires a CUDA-compatible GPU for inference, training requires significant GPU resources plus downloading large pre-trained model files separately.

No license information was mentioned in the explanation.

So what is it?

This is the research code released by OpenAI alongside a 2021 paper showing that diffusion models could produce higher-quality images than GANs, which had been the dominant approach for AI image generation. Diffusion models work by learning to gradually remove noise from a random starting image until a realistic picture emerges. This repository added two important improvements over OpenAI's earlier diffusion work: classifier guidance and architecture refinements. Classifier guidance is a technique where a separately trained image classifier is used during the image generation process to steer the output toward a specific category. For example, you can tell the model to generate an image that looks like a particular class of object, and a classifier running alongside the generator nudges each step in that direction. Adjusting a scale parameter controls how strongly the classifier influences the output, trading off diversity for accuracy to the target class. The repository provides pre-trained model weights for several image sizes: 64x64, 128x128, 256x256, and 512x512. There are also upsampler models that take a low-resolution generated image and increase its resolution. Additionally, models trained on LSUN datasets (bedroom, cat, and horse scenes) are available for download. To use the code, you download the model files and run Python scripts with command-line flags specifying the model architecture and sampling settings. The README includes exact commands for each pre-trained model. Training your own models is also supported, with scripts for both standard diffusion training and classifier training. This repository is primarily a research artifact. It requires familiarity with Python and running scripts from a terminal. No graphical interface is provided.

Copy-paste prompts

Prompt 1
I downloaded the guided-diffusion 256x256 model weights from OpenAI. Show me the exact Python command to run classifier-guided sampling and generate images of dogs with a guidance scale of 10.
Prompt 2
How do I adjust the classifier guidance scale parameter in openai/guided-diffusion to control the trade-off between output diversity and accuracy to a target class?
Prompt 3
I want to train my own diffusion model on my image dataset using the openai/guided-diffusion codebase. Which training script do I use, what dataset format is expected, and what GPU requirements should I plan for?

Frequently asked questions

What is guided-diffusion?

OpenAI's 2021 research code for generating high-quality images using diffusion models with classifier guidance, includes pre-trained models at multiple resolutions and scripts to run or train your own.

What language is guided-diffusion written in?

Mainly Python. The stack also includes Python, PyTorch, CUDA.

What license does guided-diffusion use?

No license information was mentioned in the explanation.

How hard is guided-diffusion to set up?

Setup difficulty is rated hard, with roughly 1day+ to a first successful run.

Who is guided-diffusion for?

Mainly researcher.

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