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What is science-skills?

google-deepmind/science-skills — explained in plain English

Analysis updated 2026-07-03 · repo last pushed 2026-07-01

2,202PythonAudience · researcherComplexity · 2/5ActiveSetup · moderate

In one sentence

A collection of plug-and-play skill packs that give AI agents specialized knowledge for scientific research across genomics, chemistry, and biology, grounding answers in real scientific databases.

Mindmap

mindmap
  root((repo))
    What it does
      Scientific skill packs
      Queries 30-plus databases
      Grounds AI in real data
    Tech stack
      Python
      uv package manager
    Use cases
      Genomic data analysis
      Compound lookups
      Literature search
    Audience
      Researchers
      Scientists
      Students
    Integration
      Google Antigravity
      Custom skill support
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Code map

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filefunction / class

What do people build with it?

USE CASE 1

A genetics researcher analyzes genomic data using a skill connected to AlphaGenome.

USE CASE 2

A pharmacologist looks up chemical compound information through specialized AI agent skills.

USE CASE 3

A student searches scientific literature using an AI agent grounded in real research databases.

USE CASE 4

A lab creates custom skill packs for niche research needs and loads them into a personal directory.

What is it built with?

Pythonuv

How does it compare?

google-deepmind/science-skillsfacebookresearch/fairchemhughyau/academicforge
Stars2,2022,1732,095
LanguagePythonPythonPython
Last pushed2026-07-012026-07-05
MaintenanceActiveActive
Setup difficultymoderatehardeasy
Complexity2/54/52/5
Audienceresearcherresearcherresearcher

Figures from each repo's GitHub metadata at analysis time.

How do you get it running?

Difficulty · moderate Time to first run · 30min

Integrates into Google Antigravity and some skills require API keys for certain databases, which the agent helps users obtain.

No license information was provided in the repository explanation, so usage rights are unknown.

So what is it?

Science Skills is a collection of add-on capabilities that give AI agents specialized knowledge for scientific research. Think of it as a toolbox an AI can use to help with tasks in genomics, structural biology, chemistry, and literature search, drawing on data from over 30 established databases and tools. Each skill is a package of instructions, helper scripts, and reference material. When an AI agent equipped with these skills receives a scientific question, it reads the skill's instructions and uses the provided scripts to query databases like UniProt or ClinVar. The design aims to make agents more accurate by grounding their responses in real scientific data, and more efficient by reducing the amount of processing power needed to arrive at an answer. The primary audience is researchers, scientists, and students who use AI tools to accelerate their workflows. For example, a genetics researcher could use a skill connected to AlphaGenome to analyze genomic data, or a pharmacologist could use chemistry-focused skills to look up compound information. The skills integrate directly into Google Antigravity, an AI application, where users can enable the Science plugin during setup or through settings. Some skills require API keys for certain databases, and the agent guides users through obtaining them. The project is built in Python and uses a package manager called uv to handle dependencies automatically the first time a skill runs. For users who want to tailor skills to their specific needs, the repository supports customization. Rather than editing the installed plugin directly (which would get overwritten on updates), users can place modified or entirely new skills in a personal directory on their computer. This makes the system extensible for labs or individuals with niche requirements beyond the bundled offerings.

Copy-paste prompts

Prompt 1
Using the Science Skills plugin, help me query the ClinVar database for variants related to a specific gene and summarize the clinical significance of each finding.
Prompt 2
Using the chemistry skill pack, look up compound information for a molecule I provide and return its properties from the relevant scientific database.
Prompt 3
Help me create a custom skill pack for my lab's internal database, including instructions, helper scripts, and reference material that an AI agent can use to query it.
Prompt 4
Using the AlphaGenome skill, analyze this genomic sequence and explain what regions or variants are notable based on the connected database.

Frequently asked questions

What is science-skills?

A collection of plug-and-play skill packs that give AI agents specialized knowledge for scientific research across genomics, chemistry, and biology, grounding answers in real scientific databases.

What language is science-skills written in?

Mainly Python. The stack also includes Python, uv.

Is science-skills actively maintained?

Active — commit in last 30 days (last push 2026-07-01).

What license does science-skills use?

No license information was provided in the repository explanation, so usage rights are unknown.

How hard is science-skills to set up?

Setup difficulty is rated moderate, with roughly 30min to a first successful run.

Who is science-skills for?

Mainly researcher.

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